Publications

AI-guided histopathology predicts brain metastasis in lung cancer patients
Haowen Zhou*, Mark Watson*, Cory T. Bernadt, Steven (Siyu) Lin, Chieh-yu Lin, Jon H. Ritter, Alexander Wein, Simon Mahler, Sid Rawal, Ramaswamy Govindan, Changhuei Yang, Richard J. Cote
Journal of Pathology, 2024     (BibTex)     [Code]     {Data}
Brain metastases can occur in nearly half of patients with early and locally advanced (stage I–III) non-small cell lung cancer (NSCLC). There are no reliable histopathologic or molecular means to identify those who are likely to develop brain metastases. We sought to determine if deep learning could be applied to routine H&E-stained primary tumor tissue sections from stage I–III NSCLC patients to predict the development of brain metastasis.
FPM-INR: Fourier ptychographic microscopy image stack reconstruction using implicit neural representations
Haowen Zhou*, Brandon Y. Feng*, Haiyun Guo, Siyu Lin, Mingshu Liang, Christopher A. Metzler, Changhuei Yang
Optica, 2023     (BibTex)     [Project Page]     {Data}
Fourier ptychographic microscope faces challenges with long image stack reconstruction time and huge data volumes. We designed physics-based neural signal representations to tackle these challenges and facilitates remote diagnosis, and efficient data packaging.
Automatic_detection
Automatic detection of circulating tumor cells and cancer associated fibroblasts using deep learning
Cheng Shen, Siddarth Rawal, Rebecca Brown, Haowen Zhou, Ashutosh Agarwal, Mark A. Watson, Richard J. Cote, Changhuei Yang
Sci. Rep., 2022     (BibTex)
We build an all-in-focus fluorescent microscope for circulating tumor cells and cancer-associated fibroblasts detections. The system outperforms the commercialized microscope systems and achieves high performances in cell counting.
Anlysis_of
Analysis of postreconstruction digital refocusing in Fourier ptychographic microscopy
Haowen Zhou, Cheng Shen, Mingshu Liang, Changhuei Yang
Opt. Eng., 2022     (BibTex)
We applied a thorough analysis in digital refocusing mechanism for Fourier ptychographic microscopy. It explains why a simple propagation physical model cannot succeed in a post-reconstrution manner.
Dual_wave
A review of the dual-wavelength technique for phase imaging and 3D topography
Haowen Zhou, Mallik Hussain, Partha P. Banerjee
Light Adv. Manuf., 2022     (BibTex)
We surveyed dual-wavelength technique in phase imaging and 3D topography and summarized the current challenges in this field.
Non_recursive
Use of structured light in 3D reconstruction of transparent objects
Haowen Zhou, Haiyun Guo, Partha P. Banerjee
Appl. Opt., 2022     (BibTex)
Transport of phase equation is a twin equation with transport of intensity equation, derived from the Helmholtz equation. The two equations can demonstrate the entire complex optical field and help amplitude-phase imaging.
Use_of
Use of structured light in 3D reconstruction of transparent objects
Haiyun Guo, Haowen Zhou, Partha P. Banerjee
Appl. Opt., 2022     (BibTex)
A simple concept of light refraction due to a change of refractive index and curvature of the interface provides a straightforward way to reconstruct transparent phase objects with projected structured light.
Performance
Performance analysis of phase retrieval using transport of intensity with digital holography [Invited]
Haowen Zhou, Elena Stoykova, Mallik Hussain, Partha P. Banerjee
Appl. Opt., 2021     (BibTex)
Transport of intensity equation can facilitate wrapping free phase retrieval for digital holography. We compares its performance with traditional off-axis single- and dual-wavelength techniques.
Single_shot
Single-shot digital phase-shifting Moiré patterns for 3D topography
Haiyun Guo, Haowen Zhou, Partha P. Banerjee
Appl. Opt., 2021     (BibTex)
We demonstrates a simple and robust technique of Moiré topography with single-image capture and incorporating digital filtering along with a four-step digitally implemented phase-shifting method for 3D surface mapping.
Digital_corr
Digital correlation of computer-generated holograms for 3D face recognition
Haowen Zhou, Xiaomeng Sui, Liangcai Cao, Partha P. Banerjee
Appl. Opt., 2019     (BibTex)
A digital correlation method of a computer-generated hologram (CGH) can encode 3D spatial data information into a 2D hologram. We demonstrate its application in for 3D face recognition.
3D_obj
3D object recognition through processing of 2D holograms
Behzad Bordbar, Haowen Zhou, Partha P. Banerjee
Appl. Opt., 2019     (BibTex)
Digitally recorded holograms encode three-dimensional obejct information into a 2D images (hologram). This work demonstrates the correlation of the holograms as metric to reveal object topographic features.
Sulfur
Sulfur dioxide gas-sensitive materials based on zeolitic imidazolate framework-derived carbon nanotubes
Qun Li*, Jiabin Wu*, Liang Huang, Junfeng Gao, Haowen Zhou, Yijie Shi, Qinhe Pan, Gang Zhang, Yu Du, Wenxi Liang
J. Mater. Chem. A, 2018     (BibTex)
We demonstrate the synthesis of gas-sensing materials for sulfur dioxide (ZIF-67), which results in significant sensitivity, cross-selectivity and durability towards SO2 at room temperature.

Updated on Apr. 04, 2024